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The Mecke reagent is used as a simple spot-test to presumptively identify alkaloids as well as other compounds. It is composed of a mixture of selenous acid and concentrated sulfuric acid,[1] which is dripped onto the substance being tested.
The United States Department of Justice method for producing the reagent is the addition of 100 mL of concentrated (95–98%) sulfuric acid to 1 g of selenous acid. While sale to the general public is legal, it is not recommended as strong corrosives can cause permanent skin and eye damage and require extensive safety ratings. [2]
| Substance | Color |
|---|---|
| Chlorpromazine | Blackish red |
| Codeine | Very dark bluish green |
| Diacetylmorphine (Heroin) | Deep bluish green |
| DMMA | Dark brown |
| Doxepin | Very dark red |
| Dristan | Light olive brown |
| Exedrine | Dark greyish yellow |
| LSD | Greenish black |
| Mace | Dark greyish olive |
| Methylenedioxyamphetamine (MDA) | Very dark blue |
| Mescaline | Moderate olive |
| Morphine monohydrate | Very dark bluish green |
| Opium | Olive black |
| Oxycodone | Moderate olive |
| Propoxyphene | Deep reddish brown |
| PMMA | Pale olive green[3] |
| PMA | Pale olive green[3] or light green[4] |
| Sugar | Brilliant greenish yellow |
See also
Drug checking
Dille–Koppanyi reagent
Folin's reagent
Froehde reagent
Liebermann reagent
Mandelin reagent
Marquis reagent
Simon's reagent
Zwikker reagent
References
"Mecke Reagent Testing Kit (Red Label)". Dancesafe. Archived from the original on 2012-01-24. Retrieved 2012-01-26.
"Color Test Reagents/Kits for Preliminary Identification of Drugs of Abuse" (PDF). Law Enforcement and Corrections Standards and Testing Program. July 2000. Retrieved 2011-07-24.
EMCDDA (30 Mar 2011). EMCDDA Risk Assessment: Report on the Risk Assessment of PMMA in the Framework of the Joint Action on New Synthetic Drugs. Dictus Publishing. p. 54. ISBN 978-3-8433-2695-7. Retrieved 2012-01-25.
"Clarke's Analysis of Drugs and Poisons". Pharmaceutical Press. 2011. doi:10.1080/00450618.2011.620006. ISBN 978-0-85369-711-4. S2CID 71790993.
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